| 高密度脂蛋白胆固醇与冠心病的相关性研究 |
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| 引用本文： | 姚武位,陈庆伟.高密度脂蛋白胆固醇与冠心病的相关性研究[J].心血管病学进展,2009,30(2):253-256. |
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| 作者姓名： | 姚武位 陈庆伟 |
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| 作者单位： | 重庆医科大学第二临床学院老年病科,重庆,400010 |
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| 摘 要： | 高密度脂蛋白胆固醇降低是动脉粥样硬化性心血管病的独立危险因素，血浆中高密度脂蛋白胆固醇的水平与冠心病发生呈负相关，其机制包括高密度脂蛋白逆转运胆固醇、抗氧化、促纤溶、抗血栓等作用。目前对于低高密度脂蛋白胆固醇血症患者的干预主要有生活方式改变，药物治疗，以及新近的生物疗法等策略，达到降低心血管事件的发生率。
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| 关 键 词： | 高密度脂蛋白胆固醇 冠心病 |
Correlation of High-density Lipoprotein Cholesterol with Coronary Heart Disease |
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| YAO Wu-wei,CHEN Qing-wei.Correlation of High-density Lipoprotein Cholesterol with Coronary Heart Disease[J].Advances in Cardiovascular Diseases,2009,30(2):253-256. |
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| Authors: | YAO Wu-wei CHEN Qing-wei |
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| Institution: | YAO Wu-wei, CHEN Qing-wei ( Department of Gerontology, The Second College of Clinical Medicine, Chongqing Medical University, Chongqing 400010, China) |
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| Abstract: | Reduced high-density lipoprotein cholesterol （ HDL-C ） is an independent risk factor of atherosclerotic cardiovascular disease. Plasma HDL-C levels have a negative correlation with coronary heart disease. Its mechanisms include HDL-C transport reversal, antioxidation, promoting fibrinolysis, anti-thrombotic, etc. Patients with low HDL-C hyperlipidemia can be treated through lifestyle changes, drugs, and recently developed biological therapies. Through these the incidence of cardiovascular events can be reduced. |
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| Keywords: | high-density lipoprotein coronary heart disease |
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