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高压氧与带血供周围神经移植对成鼠损伤脊髓诱发电位的影响
引用本文:杜全印,王爱民,郭庆山,郑世刚.高压氧与带血供周围神经移植对成鼠损伤脊髓诱发电位的影响[J].中国矫形外科杂志,2001,8(5):483-484.
作者姓名:杜全印  王爱民  郭庆山  郑世刚
作者单位:第三军医大学大坪医完野战外科研究所骨伤科,
摘    要:目的:研究高压氧对带血供周围神经移植修复成鼠损伤脊髓功能恢复的作用。方法:将40只成年Wistar大鼠作成脊髓半切损伤模型,随机分为A、B两组,A组单纯带血供周围神经移植修复脊髓损伤,B组为带血供周围神经移植后给予高压氧治疗。手术后1、2、4、8、10周进行感觉诱发电位(SEP)和运动诱发电位(MEP)检查。结果:SEP和MEP潜峰时的恢复B组优于A组。结论:高压氧与带血供周围神经移植对成鼠损伤脊髓功能恢复有较好的促进作用。

关 键 词:高压氧  带血供周围神经  移植  脊髓损伤
文章编号:1005-8478(2001)05-0483-02
修稿时间:2000年9月5日

The Effect of Evoked Potentials after Vascularized Peipheral Nerve Graft and Hyperbaric Oxygen Treatment in Adult Rats after Spinal Cord Injury
DU Quan yin,WANG Ai min,GUO Qing shan,et al..The Effect of Evoked Potentials after Vascularized Peipheral Nerve Graft and Hyperbaric Oxygen Treatment in Adult Rats after Spinal Cord Injury[J].The Orthopedic Journal of China,2001,8(5):483-484.
Authors:DU Quan yin  WANG Ai min  GUO Qing shan  
Institution:DU Quan yin,WANG Ai min,GUO Qing shan,et al.Department of Orthopedics,Daping Hospital,the Third Military Medical University,Chongqing 400042
Abstract:Objective:To study the recovery of neural function of adult rats after spinal cord injury by hyperbaric oxygen(HBO)treatment and vascularized peripheral nerve(VPN)transplantation.Method:40 adult Wistar rats divided into two groups with 20 rats in each,As follows:vascularized peripheral nerve graft(Guoup A);VPH and HBO treated group(Group B).After operation,somatosensory evoked potential(SEP)and motor evoked potential(MEP)were examined.Result:The peak latencies of early waves in SEPs and MEPs of Group B were superior to Group A( P <0.05).Conclusion:HBO and vascularized peripheral nerve grafts can prompt the recovery of neural function of adult rats injured spinal cord.
Keywords:Hyperbaric Oxygen(HBO)  Vascularized peripheral nerve(VPN)  Graft  Spinal cord injury
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