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苯丙胺类药物的气相色谱及气质联用检测
引用本文:崔建芳 崔凯荣. 苯丙胺类药物的气相色谱及气质联用检测[J]. 药物分析杂志, 1994, 14(4): 3-7
作者姓名:崔建芳 崔凯荣
作者单位:中国医学科学院药物研究所,国家体委运动医学研究所
摘    要:本文报道苯丙胺等11种类似药物,用气相色谱及气质联用方法进行同时分离、检测和鉴定。志愿者尿样中母体药物及其代谢物的研究,可准确判断未知尿样中此类药物的存在。

关 键 词:苯丙胺类,代谢物,气相色谱,质谱

Identification of Amphetamines in Urine by GC and GC-MS
Cui Jianfang, Li Nong, Cui Kairong, Zhou Yi and Zhou Tonghui. Identification of Amphetamines in Urine by GC and GC-MS[J]. Chinese Journal of Pharmaceutical Analysis, 1994, 14(4): 3-7
Authors:Cui Jianfang   Li Nong   Cui Kairong   Zhou Yi  Zhou Tonghui
Affiliation:Institute of Materia Medica. Chinese Academy of Medical Sciences. Beijing 100050
Abstract:Two methods were developed for the simultaneous separation and identification of amphetamines(amphetamine. methylamphetamine. ethylamphetamine, dimethylamphetamine. mefenorex. fenproporex. amphetaminil. furfenorex. benzphetamine. clobenzorex and fenethylline). The data of gas chromatography and mass spectrometry for amphetamines and their TFA-, TMS-derivatives were reported. The free drugs and their free metabolites in human urine were identified.
Keywords:amphetamines  metabolites  GC  MS  
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