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脂肪细胞因子与胰岛素抵抗的关系及其机制研究新进展
引用本文:曾俊,杨刚毅. 脂肪细胞因子与胰岛素抵抗的关系及其机制研究新进展[J]. 成都医学院学报, 2011, 6(1): 78-82. DOI: 10.3969/j.issn.1674-2257.2011.01.022
作者姓名:曾俊  杨刚毅
作者单位:重庆医科大学附属第二医院内分泌科,重庆,400010
摘    要:脂肪组织不仅能储存脂肪,还具有重要的内分泌功能。其释放了多种脂肪细胞因子如网膜素、脂联素、肿瘤坏死因子、瘦素、抵抗素、白介素-6(IL-6)等,在肥胖、胰岛素抵抗及其相关疾病的发生发展中起着重要的作用。本文对近几年发现的与糖脂代谢关系密切的脂肪细胞因子与IR的关系及其机制进行探讨。

关 键 词:脂肪细胞因子  胰岛素抵抗  机制

Recent advances in the study of the relationship and mechanism between the adipocytokines and insulin resistance
ZENG Jun,YANG Gang-Yi. Recent advances in the study of the relationship and mechanism between the adipocytokines and insulin resistance[J]. Journal of Chengdu Medical College, 2011, 6(1): 78-82. DOI: 10.3969/j.issn.1674-2257.2011.01.022
Authors:ZENG Jun  YANG Gang-Yi
Affiliation:(Department of endocrinology,the 2nd Affiliated hospital of Chongqing Medical University,Chongqing 400010,China)
Abstract:Adipose tissue can not only store fat,but also has an important endocrine function.It release a variety of adipocytokines such as omentin,leptin,adiponectin,resistin,TNF-α,IL-6 and so on,which play an important role in development in obesity,insulin resistance and related diseases.This article discusses the relationship and mechanism between the adipocytokines which are closely related with the glucolipid metabolism and IR.
Keywords:Adipocytokines  Insulin resistance  mechanism
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