| 调制波对神经元动态模型放电影响的研究 |
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| 引用本文： | 温惠中,田学隆,欧珊,许佳,马翠.调制波对神经元动态模型放电影响的研究[J].成都医学院学报,2011,6(1):36-39. |
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| 作者姓名： | 温惠中 田学隆 欧珊 许佳 马翠 |
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| 作者单位： | 温惠中,欧珊,WEN Hui-zhong,OU Shan(第三军医大学神经生物学教研室,神经生物学重庆市市级重点实验室,重庆,400038);田学隆,TIAN Xue-long(重庆大学生物工程学院,重庆,400030);许佳,XU Jia(第三军医大学电子学与电子工程学教研室,重庆,400038);马翠,MA Cui(第三军医大学数学与生物数学教研室,重庆,400038) |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 调制波携带了比普通正弦波更多的信息,其对于神经元放电的结果也随之发生变化.本实验在建立神经元动态仿真模型的基础上探讨正弦波及调制以后的波刺激对神经元放电的影响.实验结果表明,相对于单一的刺激形式,调制波刺激能激发更为复杂的膜电位变化,其重要原因是调制波诱导了Ca2+浓度变化,从而导致膜电位更易发生放电.
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| 关 键 词： | 调制波 Chay模型 动态仿真 电刺激 |
The study of neuronal discharge in response to modulation wave stimulation |
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| Authors: | WEN Hui-zhong TIAN Xue-long OU Shan XU Jia MA Cui |
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| Institution: | 1.Third Military Medical University.a Department of Neurobiology,Chongqing Key Laboratory of Neurobiology.b Department of Electronics and Electronic Engineering.c Department of Mathematics and Mathematical Biology.Chongqing 400038,China;2.College of Bioengineering,Chongqing University,Chongqing 400030,China) |
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| Abstract: | Modulated wave carries more information than the sine wave,and their results for the neuron are different.In this study,dynamic simulation model of neuron was set up and modulation sine wave stimulation was inserted.The results showed that compared with a single stimulus,the membrane potential was more complicated.The important reason is that the Ca2＋ concentration was induced by the modulation wave,resulting in that membrane potential are more likely to discharge. |
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| Keywords: | Modulation wave Chay model dynamic simulation electrical stimulation |
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