Bladder perforation: a potential risk of early endovesical chemotherapy with mitomycin C |
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Authors: | Racioppi Marco Porreca Angelo Foschi Nazario Delicato Giampaolo Destito Antonio D'Addessi Alessandro |
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Affiliation: | Urology Department, Catholic University School of Medicine, Rome, Italy. mracioppi@tiscali.it |
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Abstract: | The use of chemotherapeutic agents in the treatment of superficial bladder cancer is well known. In particular, mitomycin C (MMC) is globally accepted also in the early treatment after an endoscopic resection. Complications related to MMC are usually scarce as a systemic absorption is quite absent, while its use is effective for the bladder recurrence reduction. In our experience we report a female patient with a bladder perforation after an early instillation of a single dose of MMC. In this case, systemic toxicity occurred requiring subintensive care for a complete repair. |
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