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The Vulnerable Elders-13 Survey Predicts 5-Year Functional Decline and Mortality Outcomes in Older Ambulatory Care Patients
Authors:Lillian Min  MD  MSHS    William Yoon  Jeff Mariano  MD    Neil S. Wenger  MD  MPH    Marc N. Elliott  PhD    Caren Kamberg  MSPH     Debra Saliba  MD  MPH
Affiliation:From the Divisions of Geriatrics;and General Internal Medicine and Health Services Research, University of California at Los Angeles, Los Angeles, California;;Virginia Commonwealth University School of Medicine;;RAND, Santa Monica, California;;Geriatrics Research, Education and Clinical Care Center, Veterans Affairs Greater Los Angeles Healthcare Systems, Los Angeles, California;;and University of California at Los Angeles/Jewish Homes Borun Center for Gerontological Research, Los Angeles, California.
Abstract:OBJECTIVES: To test the predictive properties of the Vulnerable Elders-13 Survey (VES-13) a short tool that predicts functional decline and mortality over a 1- to 2-year follow-up interval over a 5-year interval.
DESIGN: Longitudinal evaluation with mean follow-up of 4.5 years.
SETTING: Two managed-care organizations.
PARTICIPANTS: Six hundred forty-nine community-dwelling older adults (≥75) enrolled in the Assessing Care of Vulnerable Elders observational study who screened positive for symptoms of falls or fear of falling, bothersome urinary incontinence, or memory problems.
MEASUREMENTS: VES-13 score (range 1–10, higher score indicates worse prognosis), functional decline (decline in count of 5 activities of daily living or nursing home entry), and deaths.
RESULTS: Higher VES-13 scores were associated with greater predicted probability of death and decline in older patients over a mean observation period of 4.5 years. For each additional VES-13 point, the odds of the combined outcome of functional decline or death was 1.37 (95% confidence interval (CI)=1.25–1.50), and the area under the receiver operating curve was 0.75 (95% CI=0.71–0.80). In the Cox proportional hazards model predicting time to death, the hazard ratio was 1.23 (95% CI=1.19–1.27) per additional VES-13 point.
CONCLUSION: This study extends the utility of the VES-13 to clinical decisions that require longer-term prognostic estimates of functional status and survival.
Keywords:vulnerable elder    functional decline    survival
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