食管贲门癌脉管瘤栓与病理相关因素分析

背景与目的:脉管瘤栓是恶性肿瘤的一种常见现象,据文献报道,胃癌、乳癌有脉管瘤栓及食管癌淋巴结阴性,而有脉管瘤栓者,预后较差。而影响脉管瘤栓生成因素报道较少,本研究旨在探讨影响食管贲门癌脉管瘤栓与病理的相关因素之间的关系。方法:对59例有脉管瘤栓的食管贲门癌病例进行了脉管瘤栓与肿瘤浸润深度(T)、淋巴结转移数目(N)和癌细胞分化程度之间的关系分析。结果:脉管瘤栓与病理的几个因素关系,①肿瘤浸润深度:T1、T2、T3间比较无显著性差异(P>0.05),T4与T1、T2、T3比较差异则具有非常显著的意义(P<0.01);②淋巴结转移数目越多与脉管瘤栓的发生率越高,统计学处理有显著性意义(P<0.01);③癌细胞分化程度低/未分化的较高/中分化的脉管瘤栓发生率高(P<0.01)。结论:食管贲门癌的脉管瘤栓与临床病理的肿瘤浸润深度及淋巴结转移数目和细胞低分化有相关关系。

Relationship between carcinoma cell embolus of esophageal or cardiac cancer and its clinical pathology

Background &Objective:Carcinoma cell embolus is a common pathological phenomenon in malignant tumors.However,there was few reports about the factors that affect the f ormation of carcinoma cell embolus.This study was designed to investigate the relatio nship between carcinoma cell embolu s of esophageal or cardic cancer and i ts clinical pathology.Method:To analyze the relations among carcinoma cell embolus,tumor invasion depth lymph node metastasis number,and cell differentiation in59patients with esophageal cancer a nd cardic cancer.Results:The relationship between carcinoma cell embolus and its forma tion factors were reflected as follo w,there was no obvious difference am ong T1,T2,T3(P>0.05),and,quite obvious difference betw een T4and T1,T2,T3(P<0.01).Carcinoma cell embolus is related t o lymph node metastasis numbers in dir ect proportion and has relations with degree of carcinoma cell different iation(P<0.01).Conclusion:There was obvious relationship amon g tumor invasion depth ,numbers of ly mph node metastasis,and low-undifferentiation of carcinom a cell for carcinoma cell embolus.