| PGE1加甲钴胺治疗糖尿病周围神经病变 |
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| 引用本文： | 朱旭萍,周智广.PGE1加甲钴胺治疗糖尿病周围神经病变[J].中南大学学报(医学版),2001,26(4):343-344. |
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| 作者姓名： | 朱旭萍 周智广 |
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| 作者单位： | 中南大学湘雅二医院内分泌科 |
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| 基金项目： | 国家“九五”攻关基金资助 ( 96 90 6 0 5 0 1) |
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| 摘 要： | 目的 :观察前列腺素E1(PGE1)与甲钴胺联合应用治疗糖尿病周围神经病变 (DPN)疗效。方法 :将 72例DPN患者分为三组 ,分别予PGE1、甲钴胺治疗及其二者合用 ,共 4周 ,对其治疗效果进行比较。结果 :给予PGE1加甲钴胺治疗组DPN症状、神经传导速度改善明显好于单用PGE1或甲钴胺治疗组 (P <0 0 1)。结论 :PGE1加甲钴胺联合用药对DPN症状改善优于单用药组
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| 关 键 词： | 糖尿病性神经病变 前列腺素E类 甲钴胺类 治疗应用 |
| 文章编号： | 1000-5625(2001)04-0343-02 |
| 修稿时间： | 2001年1月10日 |
Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy |
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| ZHU Xu ping,ZHOU Zhi guang.Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2001,26(4):343-344. |
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| Authors: | ZHU Xu ping ZHOU Zhi guang |
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| Institution: | (Instirute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011, China) |
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| Abstract: | Objective To observe the clinical effect of combined treatment of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy(DPN). Methods Seventy two patients of DPN were divided into 3 groups, they were given the drug of prostaglandin E1 (PGE1), mecobalamin, PGE1 plus mecobalamin (combined therapeutic group) and compared the therapeutic effects respectively. Results The improvement of DPN symptoms and nerve conducting speeds of combined therapeutic group was obviously better than that of the single PGE1 group or mecobalamin group(P<0 01). Conclusion combined therapy of PGE1 and mecobalamin is better than each of single drug for improvement of DPN symptoms. |
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| Keywords: | diabetic neuropathies prostaglandins E methylamines therapeutic use |
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