地佐辛复合丙泊酚联合局部麻醉在输卵管结扎术中的应用

目的：探讨地佐辛复合丙泊酚联合局部麻醉在无痛输卵管结扎术中的麻醉效果及安全性。方法：选取2013年1月-2014年4月在本院行无痛输卵管结扎术的100例妇女（ASAⅠ~Ⅱ级），按照随机数字表法将其分为D组和F组各50例。D组给予地佐辛复合丙泊酚联合局麻，F组（对照组）给予芬太尼复合丙泊酚联合局麻。观察两组手术的麻醉效果、术中体动、呼吸循环抑制、术后VAS评分、术后恶心、呕吐、头晕的发生情况。结果：两组的手术麻醉效果评分、术后受术者VAS评分、术中体动比较差异均无统计学意义（P〉0.05）。D组术中呼吸抑制发生率明显低于F组，术后4h内恶心、呕吐、头晕发生率均明显低于F组，差异均有统计学意义（P〈0.05）。结论：局麻条件下，地佐辛复合丙泊酚用于输卵管结扎术的效果与使用芬太尼复合丙泊酚的麻醉效果相当，但地佐辛组呼吸抑制及术后恶心、呕吐、头晕发生率明显低于芬太尼组。提示地佐辛复合丙泊酚联合局部麻醉应用在输卵管结扎术中的麻醉效果确切，安全性高，值得临床推广。

The Application of Dezocine Combined with Propofol for Local Anesthesia in Tubal Ligation

Objective：To investigate the anesthetic effect and safety of Dezocine combined with Propofol for local anesthesia in the painless tubal ligation. Method：100 women（ASAⅠ-Ⅱ）who underwent painless tubal ligation in our hospital from January 2013 to April 2014,they were randomly divided into the group D and the group F,50 cases in each group.The group D was given Dezocine combined with Propofol for local anesthesia,the group F（the control group） was given Fentanyl combined with Propofol for local anesthesia.The anesthetic effect,intraoperative body movement, respiratory and circulatory depression,postoperative VAS score,incidence of postoperative nausea,vomiting,dizziness of the two groups were compared.Result：There were no differences between two groups in anesthetic effect score, postoperative VAS score,intraoperative body movement（P〉0.05）.The incidence of respiratory inhibition in the group D was significantly lower than that in the group F,and within 4 hours postoperatively,incidence of nausea,vomiting and dizziness in the group D were significantly lower than those in the group F,the differences were statistically significant （P〈0.05）.Conclusion：Compared with Fentanyl combined with Propofol,Dezocine combined with Propofol has the same anesthetic effect,but with less respiratory depression and postoperative nausea,vomiting,dizziness,which suggest that the latter can be used safely in tubal ligation,is worthy of clinical promotion.