绿茶在AFB_1致大鼠肝癌作用中对免疫功能的影响 |
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引用本文: | 宁耀瑜,杨志平,张明安,覃国忠,李瑷.绿茶在AFB_1致大鼠肝癌作用中对免疫功能的影响[J].广西医科大学学报,1990(1). |
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作者姓名: | 宁耀瑜 杨志平 张明安 覃国忠 李瑷 |
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作者单位: | 广西医学院病理生理教研室,广西医学院病理生理教研室,广西医学院病理生理教研室,广西肿瘤研究所病理研究室,广西肿瘤研究所病理研究室 |
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摘 要: | 观察绿茶对注射致癌物AFB_1前(A组)、中(B组)、后(C组)3个不同时期的大鼠免疫功能的影响,结果发现,应用绿茶的3个实验组动物外周血白细胞移行抑制指数均低于对照组,其中A、B组与对照组相比,有显著差异;外周血中性白细胞吞噬率,3组均显著高于对照组,说明绿茶对AFB_1致大鼠肝癌时引起的免疫功能低下具有明显的保护作用,提示绿茶的防癌抑癌作用可能与其对免疫功能的保护有一定的关系。
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关 键 词: | 绿茶 AFB_1 免疫 |
EFFECTS OF GREEN TEA ON THE IMMUNOLOGICAL FUNCTIONS OF RATS DURING AFB_1-INDUCED HEPATOCARCINOGENESIS |
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Institution: | Department of Pathophysiology,Guangxi Medical College Ning Yaoyu,et al |
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Abstract: | This paper reported on the study of the effects of green tea on the immunological functions of rats before(A group),during(B group)and after(C group)they were exposed to AFB_1.The authors found that the percentage of phagocytosis of polymorphonuclear leucocytes was significantly higher in all 3 green tea groups than that of the control group,and also the migratory inhibition index of leucocytes was lower in all tested groups than that of the control group,in which A and B groups were much more significant (P<0.01 and P<0.05 respectively).These results indicate that green tea has some protective effect against immunoinsufficiency during AFB_1-induced hepatocarcinogenesis in rats,and suggest that cancer-prevention of the green tea may probably be mediated through its protective effects on the immune system. |
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Keywords: | Green tea Aflatoxin Immunology |
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