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低强度He-Ne激光对人红细胞血液流变特性的影响
引用本文:许锋,胡林,王现伟,曾柱.低强度He-Ne激光对人红细胞血液流变特性的影响[J].中国激光医学杂志,2006,15(2):98-101.
作者姓名:许锋  胡林  王现伟  曾柱
作者单位:1. 贵州大学理学院,光电子技术与应用省级重点实验室,贵阳市,550025
2. 北京大学基础医学院生物物理系
基金项目:中国科学院资助项目;贵州省省长基金;贵州省组织部高层次人才基金
摘    要:目的 观察不同功率的低强度He-Ne激光对正常人体红细胞流变学特性的影响。 方法 以正常人体红细胞为研究对象,测量了低强度He-Ne激光在不同照射时间(20、40、60、80和120min)、不同功率条件(2,4、6和8mw)下红细胞的变形、取向、膜流动性、膜的微黏度和渗透脆性的变化情况。 结果 照射后红细胞的变形性和膜流动性增强、渗透脆性下降。照射对红细胞流变学特性影响显著。 结论激光照射功率密度为2.55mW/cm^2,照射时间120min、照射血样为2ml时取得的照射效果最佳。

关 键 词:激光  红细胞流变特性  变形性  膜流动性  渗透脆性
文章编号:1003-9430(2006)02-0098-04
收稿时间:2005-06-20
修稿时间:2005-06-20

Effects of Low-power He-Ne Laser Irradiation on Rheological Characteristics of Human Erythrocytes
XU Feng,HU Lin,WANG Xian-wei,ZENG Zhu.Effects of Low-power He-Ne Laser Irradiation on Rheological Characteristics of Human Erythrocytes[J].Chinese Journal of Laser Medicine & Surgery,2006,15(2):98-101.
Authors:XU Feng  HU Lin  WANG Xian-wei  ZENG Zhu
Institution:1. Photoelectronic Technology and Application Laboratory, College of Science, Guiyang University, Guizhou 520025, China ;2. Department of Biophysics, Basic Medical School, Peking University
Abstract:Objective To study the rheological characteristics of erythrocytes irradiated by low-power He-Ne laser. Methods We measured some parameters of the rheological characteristics of erythmcytes irradiated with different doses of energy, such as deformability index, microviscosity, membrane fluidity, osmotic fragility,et al. Results After irradiation, the deformability index and the membrane fluidity of the erythrecytes were increased, however osmotic fragility was decreased. Our study indicated that the low-power He-Ne laser irradiation had statistically evident effects on the rheological characteristics of human red blood cells. Conclusions As for human normal erythrocytes, the optical effective condition of laser irradiation on erythrocytes obtained is 2. 55 mW/cm^2 ,120 min in 2 ml of blood sample.
Keywords:Lasers  Rheological characteristics of erythrocytes  Deformability  Membrane fluidity  osmotic fragility
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