急性脑梗死与超敏C反应蛋白的关系

目的探讨急性脑梗死患者血清超敏C-反应蛋白（hs—CRP）水平变化与脑梗死部位、严重程度及预后的关系。方法测定120例急性脑梗死患者和90名健康人血清hs—CRP的含量，按脑卒中患者临床神经功能缺损程度评分标准对患者进行评分，分组比较。结果脑梗死组血清CRP水平明显高于正常对照组（P〈0．01）。不同部位梗死患者血清hs—CRP水平比较没有差异。脑梗死轻、中、重型患者血清hs—CRP水平差异有统计学显著性（P〈0．05）。血清CRP水平越高的脑梗死患者病情越严重，临床预后差。结论血清hs—CRP水平增高与脑梗死的发生和严重程度有密切关系，而与病变部位无关。

The relationship between highly sensitive creactive protein and acute cerebral infarction

Objective To investigate the changes of the serum level of highly sensitive C- reactive protein （hs-CRP） in patients with acute cerebral infarction and its relationship to the lesions, severity of cerebral infarction. Methods The serum level of hs-CRP in 120 patients and 90 healthy persons was determined. All the patients were scored by clinic neurological deficit scale, and compared in groups. Results The serum level of hs-CRP in the patients was significantly higher than that in normal controls （ P 〈 0.01）, between natiewtn with different lesion infarction-erum hs-CRP levels had no difference.it was significantly higher in the serious group than in the middle and mild groups （ P 〈 0.05 ）. Conclusions The serum level of hs-CRP is closely correlated with the severity of cerebral infarction. Had nothing to do with the lesion localion.