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长爪沙鼠毛色遗传的研究进展及其应用前景
引用本文:刘月环,吴旧生,萨晓婴,施张奎,彭淑红.长爪沙鼠毛色遗传的研究进展及其应用前景[J].中国比较医学杂志,2003,13(2):125-128.
作者姓名:刘月环  吴旧生  萨晓婴  施张奎  彭淑红
作者单位:1. 浙江省医学科学院实验动物中心,杭州,310013
2. 浙江大学动物科学学院
摘    要:长爪沙鼠毛色的突变迄今已有11种之多,本综述了有详细特征描述的8种毛色及其遗传机制。这8种毛色中的野生色,受A位点(刺鼠毛色)和a位点(非刺鼠型黑色)控制;白色,受c位点控制,其等位基因有c^h基因(喜马拉雅型毛色)、c^chm基因(中度青紫蓝);白斑毛色,受Sp位点控制;灰色,受g位点控制;粉眼淡化色,受p位点控制。另外还有无毛突变、扩展位点的突变及淡化位点的突变等毛色出现。因长爪沙鼠是一种多用途的实验动物,其毛色研究有着较广阔的前景。

关 键 词:毛色遗传  长爪沙鼠  综述  等位基因  实验动物  药理学  寄生虫学  内分泌学  癌症
文章编号:1671-7856(2003)02-0125-04
修稿时间:2002年4月5日

The Advance and Prospects of Studies on Genetics of the Coat Colors of Mongolian Gerbil
LIU Yue-huan,WU Jiu-sheng,SA Xiao-ying,SHI Zhang-kui,PENG Shu-hong.The Advance and Prospects of Studies on Genetics of the Coat Colors of Mongolian Gerbil[J].Chinese Journal of Comparative Medicine,2003,13(2):125-128.
Authors:LIU Yue-huan  WU Jiu-sheng  SA Xiao-ying  SHI Zhang-kui  PENG Shu-hong
Abstract:Between 1970 and 2001,eleven coat mutants of Mongolian Gerbil arose in scientific laboratory and pet population.Among them,eight coat colors and their genetic mechanism were detailed in this article.The wild system includes two loci,one is A locus(coat color is agouti),the other is a locus(coat color is non-agouti or black).C system includes c locus (albino),c+h(acromelanistic albino),c chm(chinchilla medium).The white spotting mutant is controlled by Sp locus.g locus appears to a gray coat color, and p locus seems to be master of pink-eyed dilution.The hairless phenotype is only elementary introduction. No reports are on the molecular mechanism in the coat colors of Mongolian gerbil,hitherto.The gerbil is a kind of multifunctional laboratory animal;therefore studying on the field of the gerbil coat colors has wide prospects.
Keywords:Gerbillinae  Coat Color  Genetics  Population
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