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A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
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| Authors: | Mayxay Mayfong Phetsouvanh Rattanaxay Phompida Samlane Newton Paul N Khanthavong Maniphone Vannachone Bouakham Brockmans Alan White Nicholas J |
| Affiliation: | Department of Medicine, Faculty of Medical Science, National University of Laos, Laos. |
| Abstract: | Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure was high (CQ = 78%, RIII 46%; SP = 36%, RIII 15%). The treatment policy for uncomplicated P. falciparum malaria in Laos needs to be reviewed urgently. |
| Keywords: | malaria Plasmodium falciparum chemotherapy chloroquine sulfadoxine-pyrimethamine Laos |
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