| 初治除阳肺结核的耐药监测 |
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| 引用本文： | 许国章,安东明,赵敏捷,何蓉蓉,王军明,杨薇娜.初治除阳肺结核的耐药监测[J].现代实用医学,2001,13(7):336-338. |
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| 作者姓名： | 许国章 安东明 赵敏捷 何蓉蓉 王军明 杨薇娜 |
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| 作者单位： | 宁波市卫生防疫站 |
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| 基金项目： | 宁波市科委立项课题 (计划编号 990 45 )，宁波市留学回国人员科研择优基金资助项目 [甬留字 2 0 0 1( 4 )号 ] |
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| 摘 要： | 目的：建立以WHO指南为基础的结核病细菌学耐药监测系统，掌握宁波市初治涂阳肺结核的耐药水平。方法：采用整群抽样方法于1999年10月至2000年3月选择全市所有新发涂阳病例，并对其全部培养阳性的菌株进行菌型鉴定及4种抗结核药物（INH，SM，RFP，EMB）的耐药测试。结果初治耐药率为17．87％，初治耐多药率为3．40％，耐药率高低与病人的性别，年龄无关（P＞0．05）。
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| 关 键 词： | 肺结核 药物耐受性 细菌学 |
| 文章编号： | 1671-0800(2001)07-0336-03 |
| 修稿时间： | 2001年6月5日 |
Surveillance of drug resistance of pulmonary tuberculosis in Ningbo of Zhejiang province |
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| XU Guo Zhang,AN Dong Min,ZHAO Min Jie,et al..Surveillance of drug resistance of pulmonary tuberculosis in Ningbo of Zhejiang province[J].Modern Practical Medicine,2001,13(7):336-338. |
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| Authors: | XU Guo Zhang AN Dong Min ZHAO Min Jie |
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| Abstract: | Objective To establish the surveillance system for drug resistance of pulmaonary tuberculosis according to WHO guideline and to evaluate the initial drug resistance in Ningbo. Methods Cluster sampling technique was applied to continuously select all the patients with smear positive pulmonary tuberculosis from October 1999 to March 2000. Identification and susceptibility tests were done in all culture positive samples. Results The initial drug resistance was 17.87%, initial multi drug resistance 3.40%, and there were no statistical relationship of the initial drug resistance rates among the sex and age (P>0.05). Conclusion The initial drug resistance of tuberculosis ranks high in Ningbo of Zhejiang province, and the tuberculosis control program of Ningbo should be further strengthened. |
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| Keywords: | Tuberculosis Drug resistance Surveillance |
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