93例肠球菌的临床分布及耐药性分析

目的调查肠球菌的临床分布及耐药率,以指导临床合理用药。方法回顾性地分析本院4年来临床各类送检标本中肠球菌的分离情况及耐药状况。结果分离出的93株肠球菌主要来源于伤口分泌物(48.4%)、尿液(20.4%)、痰液(16.1%)、穿刺液(9.7%)、其他分泌物(5.4%)。药敏结果显示其对四环素、红霉素、氯霉素、环丙沙星、高浓度的庆大霉素和链霉素的耐药率均较高,分别为95.2%、73.0%、60.3%、54.0%、57.3%和52.4%。其对青霉素、氨苄西林耐药率均较低,分别为25.4%和20.6%。对万古霉素和替考拉宁耐药率最低。结论基层医院肠球菌的分离率及耐药率均有较明显的上升趋势,应加强基层医院的感染控制工作,同时开展肠球菌的耐药性监测和研究。

Clinical distribution and drug resistance of enterococcus in primary hospital

Objective To investigate the clinical distribution and drug resistance rate of enterococcus in order to select antimicrobial drug correctly and efficiently.Methods The isolation rate and drug resistance of enterococcus were analyzed retrospectively in our hospital in recent 4 years.Results Ninety-three strains of enterococcus were isolated,mainly from woundsecretion(48.4%),urine((20.4)%),sputum(16.1%),serouseffusion(9.7%),and others(5.4%).Antimicrobial sensitivity test showed that the drug resisdance rates were TET(95.2%),ERY(73%),CHL(60.3%),CIP(54%),GH(57.3%),STH(52.4%),PEN(25.4%),AMP(20.6%);drug resistance rate to VAN and TEI was very low.Conclusion The isolation rate and drug resistance rate has a very obvious increase in primary hospital,we should pay more intention to control nosocomial infections and monitor drug resistance of enterococcus.