糖尿病性视网膜病变的随访观察

随访糖尿病视网膜病变（ＤＲ）单纯型Ⅰ、Ⅱ、Ⅲ期８５例１４５眼，单纯型进展为增殖型糖尿病视网膜病变（ＰＤＲ）Ⅳ期者，随访２年为２１眼（１４％），５年为４９眼（３４％）；Ⅰ、Ⅱ、Ⅲ进展至Ⅳ期的发生率，Ⅲ期〉Ⅱ期，Ⅱ期〉Ⅰ期，差别有显著性（Ｐ〈０．０５）。糖尿病黄斑水肿随访年限增长而增加，初诊黄斑水肿３５眼，２年内增至４３眼，５年内增至５５眼，视网膜静脉串珠状改变，视网膜内大量微血管异常和四个象限内存在出血和／或微血管瘤是单纯型进展至ＰＤＲ的危险性病变，血糖控制不良，糖尿病病程长和高血压可能是单纯型进展至ＰＤＲ的危险性因素。为预防或减少ＤＲ致盲，应早期发现ＤＲ，并给予长期随访。

Follow-up of diabetic retinopathy

To find out the development of diabetic retinopathy(DR),the clinical data of 145eyes of 85 patients with DR were follow up.The incidence of non Proliferative diabetic retinopathy(NPDR)developing into prolifertive diabetic retinopathy(PDR)was 14%in follow up 2 years,34%in follow up 5 years.The incidence of diabetic macular edema was 24% at the onset,30%in follow up 2 years,38%in follow up 5 years.Lost control of blood sugar,the time of diabetes and hypertension may be the dangerous factors of NPDE developing into PDR.To preventing or decreasing the blindness resulted in DR,we advise early discover and closely follow up of DR.