| Abstract: | Comments on the suggested use of the progestagen-only Pill (minipill) in breast-feeding women are presented. Progestagens vary with respect to their estrogenic, progestational, and androgenic effects and, therefore, have varying effects on lactation. Megestranol acetate, .5 mg daily, or chlormadinone acetate, .5 mg daily, are without effect on lactation, while norethisterone, 35 mg, decreases the quality and quantity of milk. Thus, it is essential to indicate the specific compounds and dosages of the progestagen-only pill in any statement recommending their use in these women. It is suggested that the pharmacology of all available progestagen-only oral contraceptives be studied in order to determine the 1 with the least potency in estrogenicity or androgenicity. |
