| Abstract: | A group of 17 women in labor and 19 undergoing therapeutic abortion (a total of 36 patients aged 19 to 39) were given 1 to 5 mg Enzaprost containing prostaglandin F2 (PGF2 alpha) made by Chinoin in 500 ml iv perfusion to induce labor. The average duration of labor was 18 hours and 48 minutes (24 hours 40 minutes for primiparae and 7 hours 35 minutes for multiparae). Delivery ranged from 15 to 30 minutes. In three cases cesarean section was performed. In 14 of 19 cases of abortion, the conventional method of induction was carried out with estradiol, castor oil, calcium, and oxytocic in iv perfusion. An average dose of 2 mg Enzaprost was given to primiparae undergoing abortion, and the average time of evacuation of the uterus was 21 hours. Multiparae received 2 to 12 mg Enzaprost and the average time of expulsion of the fetus was 16 hours and 45 minutes. In 2 cases the method failed. No instances of intolerance or secondary phenomena were observed. The results confirmed the qualitative advantages of PGF2 for triggering uterine contractions: short duration of dilatation (average 11 hours and 15 minutes), simple technique, diminished side effects, no uterine hypertonia, minimal bleeding, lack of post-partum and post-abortum infection, and the minimal number of days of hospitalization. |
