Sorbitol 2.5% mannitol 0.54% irrigation solution for hysteroscopic endometrial ablation surgery

Purpose

To determine if systemic absorption of sorbitol 2.5%/mannitol 0.54% imgation solution (165 mosm·L^?1) during hysteroscopic endometrial ablation with diathermy is associated with hyponatraemia and hypoosmolality.

Methods

In 35 day surgery patients in a university hospital we measured baseline preoperative variables: serum sodium and creatinine concentrations and osmolality, haematocnt, haemoglobin, urine osmolality and sodium concentration, and weight. Fractional excretion of sodium (FE_Na) was calculated. The same observations were obtained postoperatively before discharge (one hour post resection). Volumes of intraoperative fluid imgation intravasation and penoperative intravenous fluid absorption (lactated Ringer’s solution) were estimated clinically (vdumetric).