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纳洛酮的作用机制及其在呼吸系统疾病中的临床应用
引用本文:房树娟,加孜那·托哈依. 纳洛酮的作用机制及其在呼吸系统疾病中的临床应用[J]. 国际呼吸杂志, 2005, 29(1): 812-815. DOI: 10.3760/cma.j.issn.1673-436X.2009.013.012
作者姓名:房树娟  加孜那·托哈依
作者单位:新疆医科大学第一附属医院呼吸二科,乌鲁木齐,530054;
摘    要:Naloxone is a specific synthetic opioid receptor antagonist, mainly being used for the treatment of excessive intake of morphine,the clinical application gradually proves its role in the respiratory system mainly, circulatory system, nervous system, digestive system and cardiopulmonary resuscitation, acute poisoning in the rescue. Research confirmed that naloxone can effectively curb beta-endorphin(β-EP) effect. The lifting of β-EP in chronic obstructive pulmonary disease with respiratory failure in patients with respiratory center in hibition, excite breathing. Compared with the traditional respiratory stimulants, naloxone is economic,safe,and has fewer side effects.

关 键 词:纳洛酮   阿片受体拮抗剂   临床应用   

Clinical application of naloxone in pulmonary disease
Abstract:
Keywords:NaloxoneOpioid receptor antagonistClinical application
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