| 一氧化氮对正常妊娠时子宫-胎盘-胎儿循环的调节 |
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| 引用本文： | 谢青贞,王顺芳,白骏,徐望明,杨菁. 一氧化氮对正常妊娠时子宫-胎盘-胎儿循环的调节[J]. 武汉大学学报(医学版), 1998, 0(4) |
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| 作者姓名： | 谢青贞 王顺芳 白骏 徐望明 杨菁 |
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| 作者单位： | Department of Obstetrics and Gynecolgy，Frist Affiliated Hospital，Hubei Medical University，Wuhan 430060，China |
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| 摘 要： | 通过测定１４例未孕妇及２５例正常晚孕妇母血及脐血一氧化氮（ＮＯ）的含量及部分病例子宫动脉及脐动脉最大收缩期与舒张末期血流速度之比（Ｓ／Ｄ），研究正常妊娠时母体及胎儿循环ＮＯ的变化。结果脐血ＮＯ含量显著高于母血（Ｐ＜０．０１），且与脐动脉Ｓ／Ｄ值呈现显著负相关（ｒ＝－０．５２，Ｐ＜０．０５）。说明ＮＯ对正常妊娠母体及胎儿循环均有重要调节作用
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| 关 键 词： | 妊娠；一氧化氮；子宫；动脉；脐动脉；超声多普勒 |
Nitric Oxide Levels in Maternal and Fetal Blood Circulation During Pregnancy |
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| Xie Qingzhen,Wang Shunfang,Bai Jun,et al. Nitric Oxide Levels in Maternal and Fetal Blood Circulation During Pregnancy[J]. Medical Journal of Wuhan University, 1998, 0(4) |
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| Authors: | Xie Qingzhen Wang Shunfang Bai Jun et al |
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| Abstract: | In order to clarify study whether nitric oxide (NO) levels are elevated in maternal and fetal blood circulation. Twenty five cases of normotensive pregnant women(normal pregnant group)and eighteen cases of nonpregnant women(nonpregnant group) were studied. The serum concentrations of NO - 2 in maternal peripheral and umbilical arteries were measured with greiss reagent. The peak systolic to diastolic ratio(S/D) of uterine and umbilical arteries were examined at random by color Doppler flow imaging in fourteen cases of women in normal pregnant group. The NO levels of umbilical venous serum were much higher than those of maternal serum( P <0.01). The NO levels in umbilical venous serum correlated negatively with umbilical arterial S/D ratio. The increasing of NO levels in normal pregnancy may play an important role in regulation of maternal and fetal blood circulation. |
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| Keywords: | pregnancy nitric oxide uterius artery umbilical artery doppler ultrasound |
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