Inverse relationship between cord blood adiponectin concentrations and the number of cigarettes smoked during pregnancy |
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Authors: | Pardo I M C G Geloneze B Tambascia M A Barros A A |
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Institution: | Department of Pediatrics, University of Campinas-UNICAMP, S?o Paulo, Brazil. doctorpardo@hotmail.com |
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Abstract: | BACKGROUND: Maternal smoking is linked with several neonatal metabolic disorders. Adiponectin is an adipose-specific hormone with anti-inflammatory and antiatherogenic properties. AIM: The aim of this study was to evaluate the effect of maternal smoking on cord blood adiponectin concentrations. METHODS: We evaluate the effect of maternal smoking on cord blood adiponectin concentrations comparing 14 full-term and seven preterm newborns born to mothers who smoked during pregnancy with 77 full-term and 10 preterm neonates born to non-smokers mothers. RESULTS: Maternal smoking during pregnancy was significantly associated with decreased adiponectin levels of preterm newborns (p < 0.05). CONCLUSIONS: Our findings also reveal a significant relationship between the reported number of cigarettes smoked during pregnancy and cord blood adiponectin concentrations (p = 0.01), suggesting that this association could have a causal relationship. |
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Keywords: | adiponectin smoking pregnancy |
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