Philadelphia chromosome positive chronic myelocytic leukemia with a complex translocation, t(4;9;22)(q31;q34;q11) and long survival. |
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Authors: | A D Panani A Ferti M Antonopoulos S Raptis |
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Affiliation: | Department of Haematology, Western General Hospital, Edinburgh. |
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Abstract: | An 8;21 translocation with duplication of the der(21) is described in a 72-year-old man who presented with features of chronic myelomonocytic leukemia. Progression to acute myelomonocytic leukemia occurred within one month of diagnosis. The possible prognostic significance of the t(8;21) with duplicated der(21) in myelodysplasia is discussed. |
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