| 老年性梅毒多种血清学实验的应用分析 |
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| 引用本文： | 栗群英,彭燕,陈莉,刘毓刚,胡宗海,谢静,李继红,张燕. 老年性梅毒多种血清学实验的应用分析[J]. 四川医学, 2011, 32(2): 256-257 |
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| 作者姓名： | 栗群英 彭燕 陈莉 刘毓刚 胡宗海 谢静 李继红 张燕 |
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| 作者单位： | 1. 成都军区总医院检验科,四川,成都,610083
2. 成都医学院检验系,四川,成都,610083 |
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| 摘 要： | 目的探讨酶联免疫吸附试验（TP-ELISA）、梅毒甲苯胺红不加热血清反应素试验（TRUST）和梅毒螺旋体明胶凝集试验（TPPA）在老年性梅毒检测中的应用分析。方法先用ELISA法作为临床标本的梅毒筛选,对阳性标本同时进一步做TRUST和TPPA检测。结果 ELISA法检出135例老年性梅毒阳性标本,TPPA确证119例,阳性符合率为88.14%,其中53例TRUST阳性,TPPA确证阳性;82例TRUST阴性,TPPA确证66例阳性,16例为阴性。结论 ELISA法筛查在老年性梅毒检测中存在一定比例的假阳性结果,因此阳性标本应同时加做TRUST、TPPA检测,以避免误诊和减少医疗纠纷是非常必要的。
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| 关 键 词： | 老年梅毒 酶联免疫吸附试验 梅毒甲苯胺红不加热血清反应素试验 梅毒螺旋体明胶凝集试验 |
Application analysis on different serologic tests of senile syphilis |
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| Affiliation: | LI Qun-ying,PENG Yan,CHEN Li,et al.Chengdu Military General Hospital,Chengdu,Sichuan 610083,China |
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| Abstract: | Objective To analyze the application of TP-ELISA,TRUST and TPPA in the detection of senile syphilis.Methods The syphilis samples were first screened by ELISA,and TRUST and TPPA were performed on the positive samples.Results Out of the 135 positive syphilis samples detected by ELISA,119 samples were confirmed to be positive by TPPA,the positive coincidence rate was 88.14%;the 53 positive samples by TRUST were confirmed to be positive by TPPA while 66 samples out of the 82 negative samples by TRUST were confirmed to be positive by TPPA,the other 16 samples negative.Conclusion There exists a certain ratio of false positive samples in screening senile syphilis by ELISA,it is necessary to perform TRUST and TPPA on the positive samples at the same time so as to avoid misdiagnosis and medical disputes. |
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| Keywords: | senile syphilis Enzyme-linked Immunosorbent Assay （ELISA） syphilis toluidine red unheated serum reagin test （TRUST） treponema pallidum particle assay （TPPA） |
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