吸附法无肝素透析在高危出血倾向患者中的应用

目的比较吸附法无肝素与普通肝素在常规血液透析抗凝中的有效性和可行性。方法 61例高危出血倾向的血液透析患者分别用吸附法无肝素和普通肝素抗凝进行自身前后对照,观察透析器和透析管道的凝血状态,凝血酶时间（TT）和活化部分凝血酶时间（APTT）,透析前后血肌酐（Scr）、尿素氮（BUN）。结果两组患者均能顺利完成4h的透析,透析器和透析管道凝血程度两组差异无统计学意义（P〉0.05）。TT、APTT在吸附法无肝素组透析前和透析后没有变化,而普通肝素组透析后比透析前明显延长（P〈0.001）SUN、SCr两组透析后比透析前明显降低,而两组间的变化。结论吸附法无肝素透析在高危出血倾向患者中能安全,有效的进行。

Application of adsorption no heparin dialysis patents of high risk tendency to blood

Objectives To compare the effectiveness and feasibility of adsorption on heparin dialysis with those of common heparin dialysis in the anticoagulation of conventional hemodialysis.Methods 61cases of patients of high risk tendency to blood were compared with auth-control.Results The thrombin time and activated part thrombin time had no changes before and after adsorption no heparin dialysis,but was obviously elongated after common heparin dialysis（P0.001）.Conclusions Adsorption no heparin dialysis is safe and effective for patients of high risk tendency to blood.