| 新型抗凝和抗血小板新药——重组水蛭素 |
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| 引用本文： | 黄震华. 新型抗凝和抗血小板新药——重组水蛭素[J]. 中国新药与临床杂志, 2003, 22(5): 309-312 |
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| 作者姓名： | 黄震华 |
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| 作者单位： | 上海第二医科大学附属第九人民医院,心血管病研究室,上海,200011 |
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| 摘 要： | 水蛭素是一种兼有抗血小板聚集和抗凝作用的药物 ,重组水蛭素具有更强的药理作用和更少的不良反应。本文对重组水蛭素及其主要代表药物lepirudin的药理作用、药动学、临床应用等作一介绍
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| 关 键 词： | 水蛭素 血小板聚集 血栓形成 药动学 |
| 文章编号： | 1007-7669(2003)05-0309-04 |
A new anti-coagulation and anti-platelet aggregation drug: recombinant hirudin |
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| HUANG Zhen hua. A new anti-coagulation and anti-platelet aggregation drug: recombinant hirudin[J]. Chinese Journal of New Drugs and Clinical Remedies, 2003, 22(5): 309-312 |
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| Authors: | HUANG Zhen hua |
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| Abstract: | Hirudin is a drug that has both anti platelet aggregation and anti coagulation effect. To compare with hirudin, recombinant hirudin has more potent effect and less adverse reaction. In this article, the pharmacology, pharmacokinetics, and clinical use of recombinant hirudin and its representative drug——lepirudin are introduced. |
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| Keywords: | hirudin platelet aggregation thrombosis pharmacokinetics |
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