Campylobacter jejuni bacteremia and Guillain-Barré syndrome in a renal transplant recipient |
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Authors: | M Maccario Antonio Tarantino Eduardo Nobile-Orazio Claudio Ponticelli |
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Institution: | (1) Division of Nephrology and Dialysis, IRCCS Ospedale Maggiore, Via della Commenda 15, I-20 122 Milan, Italy Fax: + 39 2 551 0809, IT;(2) Institute of Clinical Neurology, Centro Dino Ferrari, University of Milan, IRCCS Ospedale Maggiore, Via F. Sforza 35, I-20 122 Milan, Italy, IT |
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Abstract: | In patients who have not undergone transplantation, Guillain-Barré syndrome (GBS) is typically preceded by an acute infection
often sustained by Campylobacter jejuni. Thus far, in renal transplant recipients, only eight cases of GBS have been reported. In seven patients GBS was attributed
to cytomegalovirus infection and in the eighth patient to cyclosporin A neurotoxicity. We report here the case of a GBS in
a renal transplant recipient following C. jejuni bacteremia. The infection quickly disappeared after erythromycin and methronidazole therapy. GBS progressively evolved into
a paraparesis within 1 week. After reaching a plateau phase, the clinical status improved and the patient was able to walk
unassisted after 3 weeks. At his last check-up, 54 months later, the patient was doing well with a functioning graft and only
minimal weakness of the lower limbs.
Received: 17 February 1998 Received after revision: 7 July 1998 Accepted: 8 July 1998 |
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Keywords: | Guillain-Barré syndrome Campylobacter jejuni renal transplantation Campylobacter jejuni Guillain-Barré syndrome renal transplantation Renal transplantation Campylobacter jejuni Guillain-Barré syndrome |
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