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加味四君子汤治疗脾气虚型常年性变应性鼻炎的临床疗效研究
引用本文:唐月英,宋凯,曾屹生,杨眉峰.加味四君子汤治疗脾气虚型常年性变应性鼻炎的临床疗效研究[J].中国中西医结合耳鼻咽喉科杂志,2008,16(6):422-424.
作者姓名:唐月英  宋凯  曾屹生  杨眉峰
作者单位:福建中医学院附属第二人民医院耳鼻咽喉科,福建,350003
基金项目:福建省卫生厅中医药项目资助(wzy0624)福建省教育厅科技项目资助(JA04227)福建省自然基金资助项目  
摘    要:目的研究加味四君子汤对脾气虚型常年性变应性鼻炎患者的治疗作用。方法脾气虚型常年性变应性鼻炎患者60例,随机分为实验组、西药对照组,每组各30例;另设缝康对照组30例。观察2组治疗前后总体疗效、血清IL-4、IL-12及IFN-Y值变化有无显著性差异。结果①临床疗效上,实验组显著优于西药对照组(P〈0.05);②治疗前实验组、西药对照组血清IL-4明显高于健康对照组,IFN—Y、IL-12明显低于健康对照组,(P〈0.01);③治疗后,实验组、西药对照组血清IL.4均下降,血清IFN-y均上升,实验组明显优于西药对照组(P〈0.01);实验组治疗后血清IL—12明显升高,治疗前后有非常显著的差异(P〈0.01),西药对照组血清IL-12治疗前后无显著差异(P〉0.05)。结论加味四君子汤对脾气虚型常年性变应性鼻炎具有较好的临床疗效,临床上值得推广.

关 键 词:变应性鼻炎  加味四君子汤  疗效  临床研究

Clinical observation on the therapeutic effect of Supplemented Four Gentlemen Decoction on perennial allergic rhinitis in the pattern of Spleen-Qi deficiency
TANG Yueying,SONG Kai,ZENG Yisheng,YANG Meifeng.Clinical observation on the therapeutic effect of Supplemented Four Gentlemen Decoction on perennial allergic rhinitis in the pattern of Spleen-Qi deficiency[J].Chinese Journal of Otorhinolaryngology of Integrated Traditional and Western Medicine,2008,16(6):422-424.
Authors:TANG Yueying  SONG Kai  ZENG Yisheng  YANG Meifeng
Institution:TANG Yueying,SONG Kai,ZENG Yisheng,YANG Meifeng The Second Affiliated Hospital of Fujian TCM University,Fuzhou,350003,China
Abstract:Objective To investigate the therapeutic effect of Supplemented Four Gentlemen Decoction(DGD)on perennial allergic rhinitis(PAR)in a Spleen-Qi deficiency pattern(SQDP)based on a clinical trial.Methods Included in this study were 60 cases with PAR in SQDP,randomly divided into treating group(TG)treated by DGD and controlling group(CG)treated only by chemical drugs, with 30 cases in each group.Furthermore,serum samples were taken from these cases before and after the therapy respectively to detect the changes...
Keywords:Allergic rhinitis  Supplemented Four Gentlemen Decoction  Therapeutic effect  Clinical observation  
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