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Tuberculose compliquée d’un syndrome hémophagocytaire ou syndrome d’activation macrophagique |
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| Authors: | J. Sandrini A.-B. Beucher M.-C. Rousselet M. Gardembas C. Lavigne |
| Affiliation: | 1. Département de médecine interne et gérontologie, CHU d’Angers, 4, rue Larrey, 49933 Angers cedex 9, France;2. Département de pathologie cellulaire et tissulaire, CHU d’Angers, 4, rue Larrey, 49933 Angers cedex 9, France;3. Hématologie clinique, CHU d’Angers, 4, rue Larrey, 49933 Angers cedex 9, France |
| Abstract: | IntroductionThe hemophagocytic syndrome is rare and sometimes associated with tuberculosis.ObservationWe report the case of a 30-year-old migrant from Congo presenting with a recurrent right pleuropneumonia, cachexia and night sweat. Blood tests revealed bicytopenia with a normal myelogram. Thorax CT-scan showed large mediastinal lymph nodes and pleuritis. Mediastinal lymph node biopsy concluded to granulomatosis lymphadenopathy with necrosis and bone marrow biopsy suggested hemophagocytic syndrome. The outcome was favorable with antibiotics and corticosteroids. |
| Keywords: | Syndrome d&rsquo hé mophagocytose Tuberculose extrapulmonaire Histiocytose |
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