应用Onyx-18行血管内栓塞脑动静脉畸形的临床分析

目的探讨应用Onyx-18血管内栓塞脑动静脉畸形的临床治疗经验。方法回顾性分析我科近5年来应用Onyx-18治疗脑动静脉畸形患者16例,就其临床表现、影像学、治疗策略及结果进行临床研究。结果Spetzler分级：Ⅱ级3例,Ⅲ级4例,Ⅳ级7例,Ⅴ级2例。16例患者中共进行20次栓塞,完全栓塞5例（31.2%）,90%栓塞5例（31.2%）差6例。7例患者出现术后头痛,给予甘露醇脱水后症状缓解;3例出现一过性肢体偏瘫、麻木,给予相应处理后其中3例完全恢复;2例出现一过性言语不利,对症处理后症状消失;2例发生微导管拔管失败,滞留体内,术后其中1例患者出现残留右上肢轻瘫。所有患者随访6~36个月,经全脑血管造影证实未发现畸形血管团再通现象。13例格拉斯哥预后评分（GOS）=5;1例GOS=4;2例GOS=3。结论Onyx-18行血管内栓塞脑动静脉畸形安全可行,在临床上能够取得令人满意的脑血管畸形治愈率,可以有效将大的血管畸形减容,为进一步治疗创造条件。熟练掌握栓塞操作技巧及预防措施,可以使脑动静脉畸形获得更高的治愈率。

Clinical analysis of endovascular treatment in cerebral arteriovenous malformation with Onyx-18

Objective To explore the clinical experience of application of Onyx-18 used in endovascular embolization treatment of cerebral arteriovenous malformation.Methods Retrospective analysis was carried out on the application of Onyx-18 in our department for the treatment of 16 cases of cerebral arteriovenous malformation from 5 years last.The analysis mainly focused on clinical manifestation,imaging,treatment strategy and clinical result.Results According to Spetzler classification,3 cases were ranked as grades ...