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Impact of SLCO1B1 521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high‐dose methotrexate |
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| Authors: | Hua‐Nian Zhang BS Xue‐Lian He PhD Cheng Wang BS Yang Wang BS Yu‐Jun Chen MD Jian‐Xin Li BS Chang‐He Niu MD Ping Gao MD |
| Affiliation: | 1. Department of Clinical Pharmacology, Wuhan Children's Hospital, , Hubei, China;2. Department of Clinical Research Center, Wuhan Children's Hospital, , Hubei, China;3. Department of Clinical Pharmacology, Children's Hospital of Su Zhou University, , Jiangsu, China;4. Department of Hematology, Wuhan Children's Hospital, , Hubei, China |
| Abstract: | |
| Keywords: | acute lymphoblastic leukemia leucovorin rescue methotrexate relapse SLCO1B1 polymorphism toxicity |