| 基于斑马鱼模型的中药代谢研究思路与方法 |
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| 引用本文： | 韦英杰,宁青,贾晓斌,龚祝南. 基于斑马鱼模型的中药代谢研究思路与方法[J]. 中草药, 2009, 40(7): 1009-1011 |
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| 作者姓名： | 韦英杰 宁青 贾晓斌 龚祝南 |
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| 作者单位： | 1. 江苏省中医药研究院中药新型给药系统重点实验室,国家中医药管理局名方适宜剂型重点研究室,江苏,南京,210028
2. 南京师范大学生命科学学院新药中心,江苏省分子医学生物技术重点实验室,江苏,南京,210097 |
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| 基金项目： | ,江苏省中医药领军人才计划,公益性行业科研专项基金 |
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| 摘 要： | 通过查阅国内外文献,概述中药代谢研究方法的现状及不足.分析模式生物斑马鱼中药代谢模型的依据,并提出该模型的建立思路与方法.模式生物斑马鱼代谢模型有望为中药代谢研究提供一种简单的、模式的、生物的、系统的、高效的新方法,对提高我国中药体内过程的研究水平,推动中药现代化进程具有重要意义.
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| 关 键 词： | 斑马鱼 中药代谢 思路与方法 中医药现代化 |
| 收稿时间： | 2009-02-06 |
Thoughts and methods for metabolic study of Chinese materia medica based on zebrafish model |
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| WEI Ying-jie,NING Qing,JIA Xiao-bin and GONG Zhu-nan. Thoughts and methods for metabolic study of Chinese materia medica based on zebrafish model[J]. Chinese Traditional and Herbal Drugs, 2009, 40(7): 1009-1011 |
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| Authors: | WEI Ying-jie NING Qing JIA Xiao-bin GONG Zhu-nan |
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| Abstract: | Access to domestic and foreign literatures, the status and lack of metabolic study on Chinese materia medica (CMM) have been overviewed; The basis for establishing the zebrafish metabolic model of CMM has been analyzed; The thoughts and methods for the establishment of the model have been put forward. The metabolic model of zebrafish could be expected to provide a simple, model, biological, systematic, and efficient new method for CMM metabolic study. It is of great significance to enhance the research level of physiological disposition of CMM and to accelerate the modernization process of CMM. |
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| Keywords: | zebrafish metabolism of Chinese materia medica thought and method modernization of tradilional Chinese medicine |
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