| 澳洲茄边碱的抗肿瘤活性研究进展 |
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| 引用本文： | 杨丽杰,张春梅,赵鹤,李宛泽,王奇,杨一鸣,费瑞.澳洲茄边碱的抗肿瘤活性研究进展[J].中国现代应用药学,2023,40(5):705-711. |
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| 作者姓名： | 杨丽杰 张春梅 赵鹤 李宛泽 王奇 杨一鸣 费瑞 |
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| 作者单位： | 吉林大学基础医学院,吉林大学基础医学院,吉林大学基础医学院,吉林大学基础医学院,吉林大学基础医学院,吉林大学基础医学院,吉林大学基础医学院 |
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| 基金项目： | 白英的抗炎活性成分及以TLR4为靶点的相关机制研究 |
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| 摘 要： | 澳洲茄边碱是从茄科植物中分离出来的，对多种肿瘤细胞均有显著抑制作用的小分子类固醇生物碱。由于其作用效果显著且具备绿色天然和不良反应低的特点，在结构上也具有明显优势，因而在临床各类癌症治疗方面有着巨大的应用价值和前景。本文对澳洲茄边碱在抗肿瘤中的应用进行了全面总结，期望为后续该产物的相关研究和进一步应用提供更多资料。
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| 关 键 词： | 甾体生物碱 澳洲茄边碱 生物活性 抗肿瘤 |
| 收稿时间： | 2022/4/28 0:00:00 |
| 修稿时间： | 2022/9/1 0:00:00 |
Research Progress on Anticancer Activity of Solamargine |
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| YANG Lijie,ZHANG Chunmei,ZHAO He,LI Wanze,WANG Qi,YANG Yiming,Fei Rui.Research Progress on Anticancer Activity of Solamargine[J].The Chinese Journal of Modern Applied Pharmacy,2023,40(5):705-711. |
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| Authors: | YANG Lijie ZHANG Chunmei ZHAO He LI Wanze WANG Qi YANG Yiming Fei Rui |
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| Institution: | College of Basic Medical Sciences, Jilin University,College of Basic Medical Sciences, Jilin University,College of Basic Medical Sciences, Jilin University,College of Basic Medical Sciences, Jilin University,College of Basic Medical Sciences, Jilin University,College of Basic Medical Sciences, Jilin University,College of Basic Medical Sciences, Jilin University |
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| Abstract: | Solamargine is a small steroid alkaloid isolated from solanaceae, which has significant inhibitory effect on a variety of cancer cells. Due to its remarkable effect, natural characteristics and low side effects, and obvious advantages in structure, it has great application value and prospect in clinical treatment of various types of cancer. In this review, the application of solamargine in cancer field was summarized comprehensively, providing more information for the subsequent research and further application of solamargine. |
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| Keywords: | steroid alkaloid solamargine biological activity anticancer |
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