| 脑缺血再灌对小鼠学习记忆的影响及药物防护 |
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| 引用本文： | 李巍 严徽瑾. 脑缺血再灌对小鼠学习记忆的影响及药物防护[J]. 中国康复医学杂志, 1995, 10(2): 67-69 |
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| 作者姓名： | 李巍 严徽瑾 |
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| 作者单位： | 吉林医学院附院，中国医学科学院基础医学研究所 |
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| 摘 要： | 在建立及管性学习记忆障碍模型的基础上，观察脑缺血再灌对小鼠学习记忆的影响及服用尼莫地平、７６４－３、醒脑灵对其的防护作用。重复脑缺血再灌可明显的降低动物的学习和记忆能力，并可通过药物改善小鼠学习记忆障碍的程度。
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| 关 键 词： | 学习记忆障碍 脑缺血 再灌注 尼莫地 药物疗法 |
Protective effect of drug and influence of cerebral ischemia reperfusion on learning and rememberance in mice |
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| /Li Wei,Yan Huijin,Zhao Huimin,//. Protective effect of drug and influence of cerebral ischemia reperfusion on learning and rememberance in mice[J]. China Journal of Rehabilitation Medicine, 1995, 10(2): 67-69 |
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| Authors: | /Li Wei Yan Huijin Zhao Huimin // |
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| Affiliation: | /Li Wei;Yan Huijin;Zhao Huimin;// |
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| Abstract: | Based on the animal model of learning and rememberance disturbance induced by cerebral ischemia,the influence of cerebral ischemia reperfusion on learning and rememberance in mice and the protective effect of Nimodipine,764-3,Xingnaoling were observed.The results showed that repetitive ischemia might lower the ability of learning and rememberance and that Nimodipine,764-3, Xingnaoling could reduce the damage in learning and rememberance.Author's address: (Insititute of Basic Medical Sciences,Beijing,100005) |
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| Keywords: | Learning and rememberance disturbances Reperfusion of cerebral ischemia Nimodipin 764-3 Xingnaoling |
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