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眼眶NK/T细胞淋巴瘤误诊2例分析并文献复习
引用本文:陈烨,钱筠,崔晶,魏立强,刘复强. 眼眶NK/T细胞淋巴瘤误诊2例分析并文献复习[J]. 中国误诊学杂志, 2006, 6(20): 3901-3904
作者姓名:陈烨  钱筠  崔晶  魏立强  刘复强
作者单位:首都医科大学附属北京同仁医院血液科,北京,100730
摘    要:目的:综述眼眶NK/T细胞淋巴瘤的临床诊断、治疗及常见误诊原因。方法:结合文献和2例个案,对眼眶NK/T细胞的临床诊断、治疗及鉴别诊断进行分析。结果:眼眶NK/T细胞淋巴瘤是临床罕见的一类结外淋巴瘤,易误诊为眼结膜炎、眼非特异性炎症、眼眶周围软组织炎或蜂窝织炎。病理改变、免疫表型符合鼻型NK/T细胞淋巴瘤。结论:眼眶NK/T细胞淋巴瘤临床表现、免疫表型、影像学特征独特,容易误诊,临床进展快,死亡率高。

关 键 词:眶肿瘤/诊断 淋巴瘤 T细胞/诊断 误诊
文章编号:1009-6647(2006)20-3901-04
收稿时间:2006-07-02
修稿时间:2006-09-06

Literature Review of Orbital Natural Killer/T-Cell Lymphoma and Two Cases Reports
CHEN Ye,QIAN Jun,CUI Jing,et al.. Literature Review of Orbital Natural Killer/T-Cell Lymphoma and Two Cases Reports[J]. Chinese Journal of Misdiagnostics, 2006, 6(20): 3901-3904
Authors:CHEN Ye  QIAN Jun  CUI Jing  et al.
Affiliation:Department of Hematology ,Beijing Tongren Hospital Affiliated Capital Medical University ,Beijing 100730
Abstract:objective:To analyze the clinical manifestation,diagnosis,mis-diagnostic reasons and treatment method of orbital NK/T cell lymphoma.Methods:The literature was reviewed and 2 patients with orbital NK/T cell lymphoma were collected.Then we analyzed the diagnosis,differential diagnosis and therapy of orbital N K/T cell lymphoma.Results:Orbital NK/T cell lymphoma was one kind of relatively rare,new reported extra-nodal lymphoma,which was usually mis-diagnosed as conjunctivitis,idiopathic orbital inflammation,periorbital area inflammation.The orbital NK/T cell lymphoma and nasal NK/T cell lymphoma shared similar stopathology,immunopathology.Conclusions:The orbital NK/T cell lymphoma shows distinctive cliniopathologic,immunophenotypic and characteristic CT or MRI manifestations.The patients are diagnosed difficultly in the early stage,presented highly aggressive clinic course and a very high lethality.
Keywords:Orbital neoplasms/diagnosis   Lymphoma ,T-cell/diagnosis   Diagnostic errors
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