| 代谢组学与中药现代化 |
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| 引用本文： | Liang YZ,Yu Y,Yi ZB,Yi LZ,Wang P,Wang YL. 代谢组学与中药现代化[J]. 中国医学科学院学报, 2007, 29(6): 823-826 |
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| 作者姓名： | Liang YZ Yu Y Yi ZB Yi LZ Wang P Wang YL |
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| 作者单位： | 1. 中南大学,中药现代化研究中心,长沙,410083
2. 甘肃中医学院药学系,兰州,730000 |
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| 摘 要： | 近年来得以飞速发展的系统生物学,尤其是代谢组学的高通量、整体性的研究技术和研究思路,对中药方剂中活性物质的分析方法及其代谢产物的药代动力学分析提供了新思路和新方法。此外,代谢组学的研究思路,将为从现代科学的基础上解释中药的整体作用机制提供新方法;而代谢组学的研究成果,则可能为建立新型的基于代谢组学的中药药效评价的技术平台作出贡献。
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| 关 键 词： | 代谢组学 中药现代化 色谱指纹图谱 模式识别 |
| 文章编号： | 1000-503X（2007）06-0823-01 |
| 收稿时间： | 2007-07-11 |
| 修稿时间： | 2007-07-11 |
Metabonomics and the modernization of traditional Chinese medicine |
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| Liang Yi-Zeng,Yu Yan,Yi Zhi-Biao,Yi Lun-Zhao,Wang Ping,Wang Ya-Li. Metabonomics and the modernization of traditional Chinese medicine[J]. Acta Academiae Medicinae Sinicae, 2007, 29(6): 823-826 |
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| Authors: | Liang Yi-Zeng Yu Yan Yi Zhi-Biao Yi Lun-Zhao Wang Ping Wang Ya-Li |
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| Affiliation: | Research Center of Research of Modernization of Traditional Chinese Medicine, Central South University, Changsha 410083, China. yizeng_liang@263.net |
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| Abstract: | The rapid development of systems biology and especially the advances in the high-throughput and comprehensive research technologies and research idea in metabonomics provide new strategies in the analysis of active components in the formula of traditional Chinese medicine(TCM) and pharmacokinetic analysis of their metabolites in vivo.Furthermore,the initiatives of metabonomics may pave a new way to explain the action mode of TCM in the light of modern sciences,while the metabonomic research achievements may contri-bute to the establishment of a new technique platform for evaluating the efficacy of the formula of TCM. |
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| Keywords: | metabonomics modernization of traditional Chinese medicine chromatographic fingerprint pattern recognition |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
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