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兔源肺孢子虫种系发育的研究进展
引用本文:李淑珍,郭增柱.兔源肺孢子虫种系发育的研究进展[J].寄生虫与医学昆虫学报,2008,15(2):103-107.
作者姓名:李淑珍  郭增柱
作者单位:首都医科大学附属北京友谊医院,北京热带医学研究所,北京,100050
摘    要:肺孢子虫属(Pneumocystis)含多种具宿主种特异性的肺孢子虫,它们可以诱导严重免疫功能低下宿主产生肺孢子虫肺炎。断乳兔可自发发生肺孢子虫肺炎,引起典型的肺部病理组织学改变。本文就兔源肺孢子虫光镜与电镜结构、基因和种系发育学特点进行综述,并与其他种肺孢子虫进行比较,从生物学与种系发育学上证据表明兔源肺孢子虫应是一新种肺孢子虫,同时也证实了肺孢子虫具有遗传多样性。

关 键 词:肺孢子虫  种系发育  遗传多样性

UPDATE ON THE PHYLOGENY OF PNEUMOCYSTIS CARINII F. SP. ORYCTOLAGI
LI Shu-Zhen,GUO Zeng-Zhu.UPDATE ON THE PHYLOGENY OF PNEUMOCYSTIS CARINII F. SP. ORYCTOLAGI[J].Acta Parasitologica et Medica Entomologica Sinica,2008,15(2):103-107.
Authors:LI Shu-Zhen  GUO Zeng-Zhu
Institution:LI Shu-Zhen GUO Zeng-Zhu ( Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital Affiliated to Capipital University of Medical Sciences China, Belling 100050, China )
Abstract:The genus Pneumocystis includes numerous host-specific species that are able to induce severe pneumonitis,especially in severely immunocompromised hosts.Rabbits at weaning can develop spontaneous PCP which is natural Pneumocystis infection provoking typical lung histopathological changes.The article reviewed current knowledge about the morphology,ultrastructure,gene and phylogeny features of Pneumocystis carinii f.sp.oryctolagi,and compared with other Pneumocystis species.A new taxon,Pneumocystis oryctolagi,should be defined on the genotypic,phylogenetic and phenotypic bases.This paper also demonstrates that Pneumocystis spp.has genetic diversity.
Keywords:Pnemocystis  Phylogeny  Genetic diversity
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