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131Ⅰ治疗非Graves'甲状腺功能亢进及非毒性甲状腺肿后诱发Graves'病
引用本文:覃伟武. 131Ⅰ治疗非Graves'甲状腺功能亢进及非毒性甲状腺肿后诱发Graves'病[J]. 国际放射医学核医学杂志, 2006, 30(6): 325-327
作者姓名:覃伟武
作者单位:530021,南宁,广西医科大学第一附属医院核医学科
摘    要:~(131)I治疗非Graves’甲亢及非毒性甲状腺肿后数月,少部分患者体内出现促甲状腺激素受体抗体并诱发Graves’病(GD),发病率在0.05%~5%之间。其发病机制假说有通过自身免疫反应介导等。通过监测体内甲状腺自身抗体水平变化、甲状腺显像,可以预测~(131)I治疗后GD的发生。其治疗方法有抗甲状腺药物治疗、再次放射性~(131)I治疗、手术治疗。

关 键 词:碘放射性同位素  放射疗法  格雷夫斯病  甲状腺功能亢进症  甲状腺肿
文章编号:1673-4114(2006)06-0325-03
修稿时间:2006-05-10

Induction of Graves'''' disease in patients with non-autoimmune hyperthyroidism or nontoxic goiter after radioiodine treatment
QIN Wei-wu. Induction of Graves'''' disease in patients with non-autoimmune hyperthyroidism or nontoxic goiter after radioiodine treatment[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2006, 30(6): 325-327
Authors:QIN Wei-wu
Abstract:Thyrotropin receptors antibodies may occur and induce Graves'disease(GD)several months after radioiodine therapy in a small number of patients with non-autoimmune hyperthyroidism or nontoxic goiter.The prevalence of radiation-induced GD is between 0.05% and 5%.The hypothesis of this disease includes induction by autoimmune reaction and others.Detection of the thyroid autoantibodise or of ~(99m)Tc pertechnetate scan can forecast the appearance of GD.Antithyroid drugs,again radioiodine therapy and surgery,are the treatments.
Keywords:Iodine radioisotopes  Radiotherapy  Graves'disease  Hyperthyroidism  Goiter
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