血源乙型肝炎疫苗免疫持久性观察

为了解血源乙型肝炎（乙肝）疫苗的免疫持久性，对澄江县1991～1995年按照0、1、6个月免疫程序完成血源乙肝疫苗接种的人群，按接种后间隔1～5年分组，每组随机抽取100名儿童，采末梢血，共得517份免疫者的血清样品．用酶联免疫吸附试验（ELISA）检测抗-HBs、HBsAg。结果表明，接种乙肝疫苗2年内抗-HBs阳性率在90％以上，以后随间隔年眼的延长而明显下降，间隔5年降至60％，人群平均保护率达78.57％．

Observation on Immune Persistence of the Plasma-derived Hepatitis B Vaccine

In order to observe the immune persistence of plasma-derived hepatitis Bvaccine in newborns in 1991~1995 in Chengjiang County, the infants were vaccinatedwith plasma-derived hepatitis B vaccine by the schedule of 0, 1, 6, months. 100 infantswere randomy selected for testing serum HBsAg and anti-HBs every year since 1991 byELISA. Altogether 517 blood samples were collected. The anti-HBs positive rate wasabove 90% and henceforth decreased obviously following the passing of the year, untilreaching 60% of the fifth year. The protective rate of the vaccinated infants was 78.57%.