| 左氧氟沙星联合卷曲霉素治疗耐多药结核疗效评价 |
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| 引用本文： | 邱建清,董学敏,王延芳,周峰.左氧氟沙星联合卷曲霉素治疗耐多药结核疗效评价[J].临床肺科杂志,2004,9(5):477-478. |
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| 作者姓名： | 邱建清 董学敏 王延芳 周峰 |
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| 作者单位： | 251700,山东省滨州市结核肿瘤医院 |
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| 摘 要： | 目的 观察左氧氟沙星 (V)联合卷曲霉素 (C)方案对耐多药结核病 (MDR- TB)的疗效。方法 132例 MDR- TB患者随机分为治疗组 6 6例和对照组 6 6例。化疗方案分别为 3VCL THZ/6 CVL,3L KZTHE/6 THL E。结果 9个月后 ,治疗组涂阳阴转率 6 7% ,培阳阴转率 72 % ;对照组涂阳阴转率 2 7% ,培阳阴转率 33%。痰菌阴转率治疗组显著高于对照组 (P<0 .0 5 )。结论 含左氧氟沙星联合卷曲霉素治疗 MDR- TB,疗效满意。
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| 关 键 词： | 左氧氟沙星 力克肺疾 耐多药结核病 治疗 |
| 修稿时间： | 2004年3月9日 |
Therapeutic effect and evaluation of levofloxacim and pasimiazid on treating MDR-TB |
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| Qiu Jianqing Dong Xuemin Wang Yanfang et al Binzhou Tuberculosis and Tumor Hospital,Shandong ,China.Therapeutic effect and evaluation of levofloxacim and pasimiazid on treating MDR-TB[J].Journal of Clinical Pulmonary Medicine,2004,9(5):477-478. |
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| Authors: | Qiu Jianqing Dong Xuemin Wang Yanfang Binzhou Tuberculosis and Tumor Hospital Shandong China |
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| Institution: | Qiu Jianqing Dong Xuemin Wang Yanfang et al Binzhou Tuberculosis and Tumor Hospital,Shandong 251700,China |
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| Abstract: | Objective To observe the therapeutic effects in the treatment of MDR-TB with levofloxacim and Capreomycin. Methods A total of 131 cases were divided into two groups in a randomized way: the study group (n=66) and the control group (n=66). The groups were 3VCLTHZ/6CVL and 3LKZTHE/6THLE for the study and control groups, respectively. Results Nine months later, the sputum negative conversion rate in smear and the rate in cuture was, respectively, 67% and 72% in the study group, 27% and 33%, respectively, in the control group. The conversion rate in the study group is significantly high than that in the control group: P<0.05.Conclusion Significant results were achieved when choosing levofloxacin and capreomycin for treating MDR-TB. |
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| Keywords: | Levofloxacin Pasiniazid MDR-TB Treatment |
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