Role of Paris PM2.5 components in the pro-inflammatory response induced in airway epithelial cells |
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Authors: | Augustin Baulig,Seema Singh,Alexandre Marchand,Roel Schins,Robert Barouki,Michè le Garlatti,Francelyne Marano,Armelle Baeza-Squiban |
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Affiliation: | 1. Univ Paris Diderot-Paris 7, Unit of Functional and Adaptive Biology (BFA) EAC CNRS 7059, Laboratory of Molecular and Cellular Responses to Xenobiotics, 5 rue Thomas Mann, case 7073, 75205 Paris Cedex 13, France;2. Particle Research, Institut für Umweltmedizinische Forschung GmbH (IUF), Auf?m Hennekamp 50, 40225 Düsseldorf, Germany;3. INSERM UMR-S 747, 45 rue des Saints-Pères, 75 270 Paris Cedex 06, France;4. Université Paris Descartes, Centre Universitaire des Saints-Pères, 45 rue des Saints pères, 75270 Paris Cedex 06, France |
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Abstract: | Particulate matter (PM) is suspected to play a role in environmentally-induced pathologies. Due to its complex composition, the contribution of each PM components to PM-induced biological effects remains unclear. |
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Keywords: | PM2.5, particulate matter with an aerodynamic diameter <2.5 μm DEP, diesel exhaust particles CB, carbon black particles 16-HBE, 16-HBE14o- cell line GM-CSF, granulocyte macrophage-colony stimulating factor PAH, polycyclic aromatic hydrocarbons EPR, electron paramagnetic resonance |
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