| 幽门螺杆菌在使用的牙刷上分布的研究 |
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| 引用本文： | 陈发明,孙海花,贾保军,邓玲玲,黄征难.幽门螺杆菌在使用的牙刷上分布的研究[J].现代口腔医学杂志,2001,15(1):39-40. |
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| 作者姓名： | 陈发明 孙海花 贾保军 邓玲玲 黄征难 |
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| 作者单位： | 1. 海军401医院口腔科
2. 海军青岛疗养院口腔科 |
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| 摘 要： | 目的：为探讨幽门螺杆菌（helicobacter pylori,Hp)的感染方式和感染途径。本实验对不同牙周情况和胃病患病情况的自愿者使用的牙刷上Hp的分布进行研究。方法 以牙刷毛基部沉积物为标本，采用聚合酶链反应（polymerase chain reaction,PCR)方法提取Hp染色体NDA，对其特异性片段进行诊断。结果：牙周状况较好者，无胃病者使用的牙刷Hp 检出率较低；并且牙刷使用时间越长，Hp在牙刷毛基部沉积物上孳生的可能越大（P＜0．01），同时牙刷的正确使用与保护对Hp检出率亦有非常显著的影响（P＜0．05），结论：牙刷上Hp的分布说明口腔可能是Hp传播的一条通道，因此牙刷使用时间不宜过长，另外养成良好的口腔卫生习惯也十分重要。
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| 关 键 词： | 幽门螺杆菌 牙刷 聚合酶链反应 口腔卫生 |
| 修稿时间： | 1999年11月2日 |
A study on the
distribution of helicobacter pylori in toothbrush |
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| CHEN Faming,SUN Haihua,JIA Baijun,et al..A study on the
distribution of helicobacter pylori in toothbrush[J].Journal of Modern Stomatology,2001,15(1):39-40. |
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| Authors: | CHEN Faming SUN Haihua JIA Baijun |
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| Institution: | CHEN Faming,SUN Haihua,JIA Baijun,et al. Department of Stomatology,Navy No.401 Hospital of PLA,Qingdao 266071 |
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| Abstract: | Objective To investigate the distribution of helicobacter pylori (Hp) and its infection in toothbrush.Methods 150 toothbrushes were studied,the deposit and food debris in the toothbrush bristle were analysed by polymerase chain reaction (PCR).Results Hp was isolated from toothbrush.The Hp positive rate was influenced by toothbrush working time,protection method,and periodontal or stomach disease.Conclusion The detection of Hp in toothbrush suggests that Hp clolnization is not restricted to the gastric mucous and this ecological niche may serve be as a possible sanctuary which may responsible for resettle of the stomach Hp.Toothbrush protecting and work time is also very important to stomach health. |
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| Keywords: | Helicobacter pylori (Hp) Toothbrush Polymerase chain reaction (PCR) |
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