Brooke-Spiegler syndrome: report of a case of multiple cylindromas and trichoepitheliomas |
| |
Authors: | Doherty Sean D Barrett Terry L Joseph Aaron K |
| |
Affiliation: | Baylor College of Medicine, Houston, Texas, USA. |
| |
Abstract: | We report a case of Brooke-Spiegler syndrome, a rare autosomal dominant disorder caused by mutations of the cylindromatosis gene (CYLD) tumor suppressor gene resulting in multiple cylindromas and trichoepitheliomas. Treatment of these patients can involve surgical excision, laser therapy, or topical applications of aspirin derivatives. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|