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凝血酶对食管癌EC109细胞增殖的影响
引用本文:邵颖,许芹芹,李淳. 凝血酶对食管癌EC109细胞增殖的影响[J]. 汕头大学医学院学报, 2010, 23(4): 209-211
作者姓名:邵颖  许芹芹  李淳
作者单位:汕头大学医学院病理学教研室;
基金项目:国家自然科学基金资助项目
摘    要:目的:探讨凝血酶对食管癌EC109细胞增殖的影响。方法:MTT比色法检测细胞增殖情况。凝血酶(终浓度1 U/mL)组和其作用于EC109细胞后收集的上清分别培养EC109细胞24、48、72 h。结果:凝血酶培养EC109细胞48 h后,细胞的490 nmOD值高于对照组(P〈0.05)。培养上清处理的各组与对照组比无统计学意义。结论:凝血酶有刺激EC109细胞增殖的作用。

关 键 词:凝血酶  EC109细胞  增殖

Effect of Thrombin on the Proliferation of Esophageal Carcinoma EC109 Cells
SHAO Ying,XU Qin-qin,LI Chun. Effect of Thrombin on the Proliferation of Esophageal Carcinoma EC109 Cells[J]. Journal of Shantou University Medical College, 2010, 23(4): 209-211
Authors:SHAO Ying  XU Qin-qin  LI Chun
Affiliation:SHAO Ying,XU Qin-qin,LI Chun(Department of Pathology,Shantou University Medical College,Shantou 515041,China)
Abstract:Objective:To investigate the effect of thrombin on the proliferation of esophageal carcinoma EC109 cells.Method:The proliferation of cultured EC109 cells was determined by MTT method.EC109 cells were cultured by thrombin(1 U/mL)and thrombin culture supernatants for 24,48,72 hours respectively.Results:Thrombin promoted the proliferation of EC109 cells significantly when cells were treated with 1 U/mL thrombin for 48 hours.There was no significant difference between all culture supernatants groups and control...
Keywords:thrombin  EC109 cell  proliferation  
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