昆明市情感障碍流行病学调查

目的:了解昆明市情感障碍患病率。方法:采用分层容量比例概率随机抽样法,应用中文版复合性国际诊断交谈检查2.1版(CIDI-2.1)对该市≥15岁的居民5033人进行访谈,调查情感障碍的患病率,分析影响情感障碍的相关因素、起病年龄及共病情况。结果:情感障碍30天患病率为0.98%,12个月患病率为1.22%,终生患病率为1.89%,单因素分析结果显示,城镇居民、离婚/分居/丧偶人群、无业者、受教育程度较高者更易患抑郁症。多因素分析结果显示,家居农村、男性可能是情感障碍的保护因素。不同情感障碍亚型起病年龄不同,90%的双相情感障碍患者在25岁以前起病,情感恶劣在50岁以前存在起病风险,重性抑郁的起病风险持续终生。患有焦虑障碍和疼痛障碍可以增高情感障碍的患病风险。结论:情感障碍患病率低于国外同类研究而与国内研究接近,城镇居民、女性、独身、无业,受教育程度较高者有较高的患病风险,是干预的重点人群。

Epidemiological survey of affective disorder in Kunming City

Objective: To investigate the prevalence of affective disorder in Kunming City. Methods: A rep-resentative sample of the Kunming general population composed of 5033 individuals aged 15 years and older was se-lecteed randomly by the method of probability proportional to size (PPS), and then was interviewed with the World Health Organization Composite International Diagnostic Interview Version 2.1 (CIDI, version 2.1).The preva-lence of affective disorder was investigated. And the relative factors, onset age and comorbid were also analyzed. Results: The 30-duy prevalence of affective disorder was 0.98%, the 12-month prevalence was 1.22%,and the lifetime prevalence was 1.89%. The results of the single factor analysis showed that the urban residents, the persons who divorced, limited divorced or lost one's spouse, and the unemployed or the higher educated were more vulnerable to depression. The results of the multifactor analysis showed that the rural residents and the males were protective factors to affective disorder. Different subunits of affective disorder had different onset ages. The onset age of 90% bipolar disorder patients was before 25 years old. The patients before 50 years old was risky to dysthy-mia. The patients with major depression had a lifetime risk of onset. Anxiety disorder and pain disorder would in-crease the risk of affective disorder. Conclusion: The findings show that the prevalence of the affective disorder is lower than the same kind survey abroad while it is close to the domestic's. More attention and intervention should been given to the urban population, the females, the singles, the unemployed, and the higher educationed.