| Abstract: | Glucocorticoids have recently been shown to acutely stimulate growth hormone secretion in man. The aim of our study was to investigate the acute effects of three graded doses of dexamethasone. Six healthy male volunteers received in random order placebo, 1, 2 or 4 mg of oral dexamethasone. Mean stimulated growth hormone levels were significantly higher after 2 and 4 mg of DEX than after 1 mg or placebo. We conclude that dexamethasone used in lower doses than previously reported appears to stimulate growth hormone release in a dose dependent manner. |
