IgA肾病68例临床与病理分析及分型治疗

目的:研究IgA肾病临床与病理特点及相互关系,观察分型治疗的疗效。方法:对68例IgA肾病患者临床和病理特点及其关系进行分析,依据其特点采用雷公藤多甙、代文、强的松等不同的治疗方案。结果:68例患者均有血尿(伴或不伴蛋白尿),病理表现重者临床表现也重。68例患者病理类型多样,以系膜增生性肾炎最多,其次为局灶节段性病变,分别占69.1%和11.8%。病理分级以Ⅱ级和Ⅲ级最多,占85.3%。分型治疗8周后显效率48.5%,有效率36.8%,无效率14.7%。结论:IgA肾病临床及病理表现多样化并具有一定的特点和联系,应采取分型治疗的原则。

Clinicopathological Study and Treatment of 68 Cases with lgA Nephropathy

Objective To investigate the relationship between clinical features and pathomorphological types in IgA nephropaty.Methods The clinical features and pathomorphological types were analyzed respectively.Different therapies were used in terms of the features.Results All the patients studied showed hematuria,with or without proteinuria.The more severe pathological rank,the more severe clinical presence.Pathologically,mesangical proliferative glomeruloneritis(69.1%)was the most frequent type,followed by focal gl...