Activation and role of natural killer cells in virus infections |
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| Authors: | C. A. Biron R. M. Welsh |
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| Affiliation: | (1) Department of Pathology and Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, 01605 Worcester, Massachusetts, USA |
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| Abstract: | Natural killer cells may play a significant role in virus infections. Virus-induced interferon activates these cells to become highly cytotoxic, and viral infections may also affect the proliferation of such cells. Non-immune mice have an apparently cellular defense mechanism which rapidly lyses implanted virus-infected cells. The evidence for NK cell involvement in viral disease is reviewed.Presented at the Fifth International congress of Virology, Strasbourg, France, 1981. |
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